The pharmaceutical company had a clinical setback earlier this year, but that's now in the rearview mirror.Over the past five years, Eli Lilly (LLY 1.43%) has outperformed the broader market, largely thanks to its progress in the GLP-1 arena. Its major breakthroughs in the field are already leading to incredible commercial success.But Lilly isn't done just yet. Recent clinical developments may set the stage for further stock-market gains, and potentially allow the drugmaker to maintain that momentum through ...

Pilot study met key 3-month efficacy endpoint with strong statistical significance (p=0.014); Revita-treated patients lost an additional 2.5% total body weight after stopping GLP-1 drugs vs. 10% regain in sham-treated patients Revita procedure demonstrated excellent safety and tolerability to date, consistent with prior clinical studies Results validate pivotal study design and reinforce Revita’s potential to be the first therapy for post-GLP-1 weight maintenance Company to host investor call and webcast to ...

试验结果概述 - 礼来公司发布头对头试验顶线结果 声称其口服GLP-1药物orforglipron在治疗2型糖尿病方面优于诺和诺德口服版Wegovy [2] - 试验主要终点为降低A1C水平（血糖指标） 礼来36mg剂量组A1C降低2.2% 诺和诺德14mg剂量组降低1.4% [3] - 次要终点体重减轻数据显示 礼来36mg剂量组平均减重9.2% 诺和诺德14mg剂量组减重5.3% [4] 数据背景分析 - 诺和诺德正在试验更高剂量25mg口服司美格鲁肽用于肥胖症治疗 远超礼来试验采用的14mg剂量 [4] - 诺和诺德Oasis 4三期试验显示 25mg剂量口服司美格鲁肽实现平均体重减少16.6% [6] - 礼来试验结果不能证明orforglipron在利润更丰厚的肥胖适应症疗效上优于口服司美格鲁肽 [7] 行业竞争态势 - 两种口服药物均未上市销售 试验结果不代表竞争格局已定 [2] - 头对头试验主要针对2型糖尿病治疗 肥胖症适应症存在不同剂量方案 [3][4][7]

Global Partners LP's recent purchase of 5,000 shares indicates a strong belief in the company's future growth.Zacks Investment Research highlights GLP as potentially undervalued, making it attractive to value investors.With a market capitalization of approximately $1.7 billion, GLP remains a significant player in the Oils-Energy sector.Global Partners LP (NYSE:GLP) is a key player in the Oils-Energy sector, which includes 240 companies and is ranked #14 in the Zacks Sector Rank. The company is involved in t ...

AUSTIN, Texas--(BUSINESS WIRE)---- $HYFT #AI--MindWalk Holdings Corp.â,,¢ ("MindWalk,†"we† or "us† ) (Nasdaq: HYFT), a Bio-Native AI company, today announced "Company,†a major advancement of its AI-designed GLP-1 therapeutics program. New insights from the Company's LensAlâ, g platform reveal a previously unrecognized connection between GLP-1 biology and a second, non- overlapping pathway central to healthy aging and systemic resilience. The findings support a first-in-class dual- pathway regimen in whi ...

This story was originally published on C-Store Dive. To receive daily news and insights, subscribe to our free daily C-Store Dive newsletter. Dive Brief: Global Partners LP has requested a court order to block the Massachusetts Department of Transportation from finalizing its deal with Applegreen to redevelop and operate 18 state highway service plazas, the convenience retailer announced last week. In a lawsuit filed in Suffolk Superior Court, Global Partners said it seeks a temporary restraining order ...

Key Takeaways Novo Nordisk's Ozempic cut major cardiovascular event risk by 23% versus Eli Lilly's Trulicity.Ozempic also showed a 25% reduction in a broader composite endpoint in the REACH study.Novo Nordisk secured EU approval to add cardiovascular benefits to the Rybelsus label.The global GLP-1 market has been in the spotlight for the past couple of years as big pharma players realize its multi-billion-dollar potential and the untapped nature. It is currently dominated by Novo Nordisk (NVO) and Eli Lilly ...

公司股价表现 - 过去12个月公司股票表现优异 是AI增强的"瑰丽7股"之外表现最佳的股票之一 [1] - 过去一个月股价上涨10% 主要受FDA可能加速审批口服GLP-1候选药物的消息推动 [2] - 过去五年股价上涨近400% 尽管最近一年半被部分交易员称为"僵尸股" [8] - 当前股价761.52美元 52周区间为623.78-939.86美元 [1] - 分析师给出的12个月目标价平均为939.61美元 较当前价格有23.73%上行空间 [3] GLP-1市场地位 - 公司是GLP-1市场领导者 该市场正在改变2型糖尿病和肥胖症的治疗方式 [1] - 口服GLP-1解决方案可能重新定义该领域的可及性和成本动态 显著扩大GLP-1市场规模 [2] - 虽然多家公司都在测试口服GLP-1解决方案 但公司进展最为领先 [4] - 诺和诺德是主要竞争对手 但公司在药物开发速度和制造规模方面仍保持优势 [8] 口服GLP-1药物进展 - FDA可能通过新推出的1-2个月快速审查流程加速审批该药物 [4] - 口服给药方式若能降低成本 可能提高保险覆盖意愿 目前用于减肥的GLP-1药物很少被保险覆盖 [5] - 口服解决方案解决了用户不喜欢或不愿处理持续针头注射的问题 [2] 制造战略与投资 - 公司战略投资270亿美元用于美国制造业 [6] - 承诺50亿美元在弗吉尼亚州建设制造工厂 提高国内口服GLP-1候选药物和肿瘤药物的生产能力 [6] - 这是公司计划在美国建设的四个新设施中的第一个 [6] - 此举解决了两党对制药供应链脆弱性的担忧 减少关税风险 并可能获得监管机构的认可 [7] 财务指标与估值 - 市盈率为49.79倍 [1] - 远期市盈率为32倍 虽然高于其他大型制药公司 但相对于历史平均水平和GLP-1药物主导地位具有良好价值 [12][13] - 股息收益率为0.79% 年度股息为6美元/股 [10][13] - 股息已连续11年增长 派息比率约为39% 具有可持续性 [10][13] 产品管线与增长动力 - 除了GLP-1药物外 公司的肿瘤学和抗体药物偶联物管线提供进一步增长机会 [11] - 美国制造重点是一个战略护城河 可多元化收入基础并降低政治和物流风险 [11] - 肥胖治疗保险覆盖的不确定性可能影响短期盈利 但长期前景保持完整 [9]

Key Takeaways ENTX unveiled promising PK data for oral GLP-2 analog OPK-8801003 in SBS.ENTX's therapy showed 15-hour half-life, 18x longer than current injection option.ENTX's oral approach could improve adherence versus burdensome daily injections.Entera Bio Ltd. (ENTX) recently reported encouraging pharmacokinetic data, underscoring the potential of its first-in-class oral GLP-2 analog therapy for patients with short bowel syndrome (SBS). The findings, presented at the 47th European Society for Clinical N ...

Accessibility StatementSkip Navigation In SURPASS-PEDS, Mounjaro met the primary and all key secondary endpoints at 30 weeks and showed sustained improvement in glycemic control and continued BMI reduction through the study's 52-week extension  The safety and tolerability profile of Mounjaro was generally consistent with previous adult studies INDIANAPOLIS, Sept. 17, 2025 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today announced detailed results from SURPASS-PEDS, the first Phase 3 trial to evaluat ...