SAN DIEGO--(BUSINESS WIRE)---- $GOSS--Gossamer Bio, Inc. (Nasdaq: GOSS), a late-stage, clinical biopharmaceutical company focused on the development and commercialization of seralutinib for the treatment of pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD), today announced it has entered into an option agreement to acquire Respira Therapeutics (Respira) and its lead product candidate, RT234, an investigational inhaled vardenafil drypowder. ...

AUSTIN, Texas--(BUSINESS WIRE)--Anebulo Pharmaceuticals, Inc. (Nasdaq: ANEB), a clinical-stage biopharmaceutical company developing novel solutions for people suffering from acute cannabinoid-induced toxicities (the "Company†or "Anebulo†), today announces the first subjects dosed in its Phase 1 single ascending dose ("SAD†) study of intravenous (IV) selonabant in healthy young adults. The study is supported by a collaborative grant from the National Institute on Drug Abuse (NIDA). First Subjec. ...

公司核心动态 - MiNK Therapeutics公司总裁兼首席执行官Jennifer Buell博士将在2025年9月23日至26日于波士顿举行的第十届CAR-TCR峰会上发表主题演讲[1] - Buell博士将在题为“审视细胞疗法在肿瘤学之外的范畴并回顾成功与失败”的全体会议上发言[2] - 发言内容将首次公布公司iNKT平台的人体数据 展示其在严重免疫衰竭中实现持久的疾病逆转和无类固醇缓解[2] - 公司将阐述其转化战略 重点介绍精准试验设计、患者分层和组织特异性靶向如何加速高负担非肿瘤适应症的开发[2] 公司技术与产品管线 - MiNK Therapeutics是一家临床阶段生物制药公司 专注于开发同种异体不变自然杀伤T细胞疗法和精准靶向免疫技术[5] - 公司专有平台旨在恢复免疫平衡 并在癌症、免疫介导疾病和肺部免疫衰竭中驱动细胞毒性免疫反应[5] - 主导在研产品agenT-797是一种现成的同种异体iNKT细胞疗法 目前正针对移植物抗宿主病、实体瘤和严重肺部免疫衰竭进行临床开发[5] - 公司同时推进基于T细胞受体的疗法和新生抗原发现工具管线 这些工具能够实现肿瘤和组织特异性免疫激活 具有广泛的应用潜力[5] - 公司的iNKT疗法采用现成方法 设计为可扩展、广泛可及 且无需HLA匹配或淋巴细胞清除即可使用[3] 行业会议与平台价值 - 第十届CAR-TCR峰会是细胞疗法领域首要的全球论坛 汇聚超过800名利益相关者 包括C级高管、顶尖科学家、投资者和监管机构[4] - 会议拥有100多名世界级演讲嘉宾和六个并行内容轨道 涵盖从发现到商业化的全过程[4] - 该峰会是工程化细胞疗法领域权威的全球性会议 展示CAR-T、TCR和iNKT细胞疗法在肿瘤学、自身免疫病等领域的最新突破[2][4]

MALVERN, Pa., Sept. 25, 2025 (GLOBE NEWSWIRE) -- Annovis Bio, Inc. (NYSE: ANVS) ("Annovis" or the “Company”), a late-stage clinical drug platform company pioneering transformative therapies for neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD), today announced the appointment of Mark Guerin, CPA, CMA, CFM, as Chief Financial Officer (CFO) to help lead the Company through a pivotal phase as buntanetap continues to show promise in late-stage clinical development. Mr. Gue ...

Peer-reviewed results from Phase 1b/2a Trial of Anti-pTau Active Immunotherapy from AC Immune Published in eBioMedicine Detailed results from completed Phase 1b/2a trial of ACI-35.030 and JACI-35.054 demonstrated that two different active immunotherapy formulations against the same target can induce a differential antibody response in individuals with early Alzheimer’s diseaseACI-35.030, developed using AC Immune’s SupraAntigen® technology, generated rapid, potent polyclonal response against pathological f ...

Revolution Medicines (RVMD) 公司及其核心产品 - 公司是一家专注于晚期临床肿瘤学研究的生物制药公司，致力于开发针对RAS成瘾性癌症的新药 [4] - 核心候选药物daraxonrasib (RMC-6236) 的最新临床试验结果支持启动其用于一线转移性胰腺导管腺癌的全球3期注册试验 [1] - 该药物作为单药治疗一线和二线转移性胰腺导管腺癌的研究结果显示，其具有可耐受的安全性以及可测量的抗肿瘤活性 [8] - 在结果公布后，公司股价大幅跃升，涨幅高达14% [8] - daraxonrasib目前正在进行多项临床试验，针对转移性胰腺导管腺癌和非小细胞肺癌，并参与针对其他实体瘤的联合疗法研究 [9] Revolution Medicines (RVMD) 的技术平台与市场潜力 - RAS突变发生在大约三分之一的人类癌症中，尤其在胰腺癌、肺癌和结直肠癌等更危险的癌症类型中非常普遍 [2] - 公司开发了一个以多种RAS(ON)抑制剂为特色的研究管线，这些抑制剂专门设计用于对抗多种致癌版本的RAS蛋白 [2] - 在RAS成瘾性癌症中，突变的蛋白质导致细胞不受控制地生长，但也为新的疗法提供了突破口，关闭RAS通路的治疗剂可能对这些癌症具有高效力 [3] - 分析师认为daraxonrasib的广谱活性优于突变选择性方法，有望成为RAS突变晚期胰腺癌的新标准疗法，并在一线非小细胞肺癌治疗中具有潜力 [10] - 公司资金充足，有望成为全球商业实体，或因尚未达成欧盟合作伙伴关系而成为主要的收购目标 [11] Revolution Medicines (RVMD) 的市场观点与估值 - 一位分析师给予公司股票“强力买入”评级，目标价为72美元，暗示一年内有63%的上涨潜力 [11] - 该股票获得了15份近期的正面分析师评价，一致共识评级为“强力买入” [11] - 股票当前价格为44.21美元，平均目标价71.24美元表明一年内有61%的上涨空间 [11] Jamf Holding (JAMF) 公司业务概览 - 公司是一家科技公司，在基于云的企业级苹果生态系统管理领域确立了领先地位，是苹果基础设施唯一企业级、垂直聚焦的安全平台 [12] - 其平台旨在帮助各种类型的组织连接、管理和保护其各类苹果产品，无需物理连接，可实现设备首次开机自动配置 [13] - 公司提供多种解决方案，包括Mac管理、安全以及针对iPhone、iPad等移动设备的管理，服务可根据用户需求定制 [14] Jamf Holding (JAMF) 的财务表现与增长 - 在2025年第二季度，公司营收同比增长15%至1.765亿美元，超出预期753万美元 [15] - 年度经常性收入增长14%，总额达到7.1亿美元 [15] - 非GAAP每股收益为0.18美元，符合预期，较去年同期每股增长0.04美元 [15] - 有机增长似乎已加速，公司继续推动显著的同比运营杠杆，预计将在2026年第四季度末成为符合“40法则”的企业 [17] Jamf Holding (JAMF) 的市场观点与估值 - 一位分析师指出其收入和ARR的强劲增长，并强调其作为收购目标的潜力，给予“买入”评级，目标价15美元，暗示39%的上涨潜力 [16][18] - 总体分析师共识评级为“适度买入”，基于11份评价（8个买入，3个持有） [18] - 股票当前价格为10.76美元，平均目标价14.20美元表明未来12个月有32%的上涨空间 [18] 当前市场并购环境 - 标普500指数在2025年上涨了14%，受人工智能热潮推动，纳斯达克指数飙升了17% [7] - 市场表现强劲时，并购交易通常会随之而来，上涨的股价为公司提供了更有价值的股票作为收购货币 [6] - 近期市场出现了大规模并购交易案例，例如谷歌以320亿美元收购云安全公司Wiz，Palo Alto Networks以250亿美元现金加股票收购CyberArk [5]

This is my third Rhythm (NASDAQ: RYTM ) article, following 06/2025's "Rhythm Pharmaceuticals: Rare Genetic Obesity Pioneer With Excellent Prospects." In Excellent Prospects , I rated Rhythm as a "Buy." It has since enjoyed a tasty ~52% bump. In this article, I will assess its forward prospectsWriting under the pseudonym "out of ignorance", I very much regard investing as a learning process. Investing failures are tuition paid. Investing successes enter the trove of lessons learned. In my Seeking Alpha artic ...

- Total non-dilutive funding of up to USD 159 million upon completion of predefined milestones, including near-term committed funding of USD 6 million Ad hoc announcement pursuant to Art. 53 LR Allschwil, Switzerland, September 25, 2025 Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, announced today that the Biomedical Advanced Research and Development Authority (BARDA), par ...

CARMEL, Ind., Sept. 24, 2025 (GLOBE NEWSWIRE) -- MBX Biosciences, Inc. (Nasdaq: MBX), a clinical-stage biopharmaceutical company focused on the discovery and development of novel precision peptide therapies for the treatment of endocrine and metabolic disorders, today announced the pricing of its upsized public offering of 11,108,055 shares of its common stock at a price to the public of $18.00 per share. The gross proceeds to MBX Biosciences from the offering, before deducting underwriting discounts and co ...

Accessibility StatementSkip Navigation SAN DIEGO, Sept. 24, 2025 /PRNewswire/ -- Robbins LLPÂ reminds stockholders that a class action was filed on behalf of persons and entities that purchased or otherwise acquired Savara Inc. (NASAQ: SVRA) securities between March 7, 2024 and May 23, 2025. Savara is a clinical-stage biopharmaceutical company focused on rare respiratory diseases. The Company's lead product candidate is MOLBREEVI (also referred to as "molgramostim"), an inhaled granulocyte-macrophage colony ...