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US FDA approves Novartis' drug for skin disease
Reuters· 2025-09-30 20:22
The U.S. Food and Drug Administration has approved Novartis' oral treatment for patients with type of chronic inflammatory skin disease, the company said on Tuesday. ...
Top 12 Blue Chip Stocks to Buy At 52-Week Lows
Insider Monkey· 2025-09-30 20:21
In this article, we will look at the Top 12 Blue Chip Stocks to Buy At 52-Week Lows.On September 30, Elyse Ausenbaugh, Head of Investment Strategy at JPMorgan Wealth Management, joined CNBC for an interview to discuss the current market rally. She noted that there is a strong momentum going forward in 2025, which is likely to continue in 2026 as well. She sees improvements in the macroeconomic environment and anticipates powerful tailwinds from significant investments in AI.She highlighted that the current ...
Pfizer strikes $70B deal with Trump to cut Medicaid drug prices, expand U.S. manufacturing under tariff threat
Fortune· 2025-09-30 20:20
Pfizer has agreed to lower the cost of prescription drugs for Medicaid under a deal struck with the Trump administration, President Donald Trump said Tuesday as he promised similar deals with other drugmakers under the threat of tariffs.Trump made the announcement at the White House alongside Pfizer CEO Albert Bourla just hours ahead of a possible government shutdown in a partisan standoff over health care and spending.Pfizer Inc., one of the largest U.S. drugmakers, produces the COVID-19 vaccine Comirnaty ...
Novartis receives FDA approval for Rhapsido® (remibrutinib), the only oral, targeted BTKi treatment for chronic spontaneous urticaria (CSU)
Globenewswire· 2025-09-30 20:15
Ad hoc announcement pursuant to Art. 53 LR Rhapsido helps to inhibit release of histamine and proinflammatory mediators by targeting BTK, offering unique approach to CSU treatment1Well-controlled disease observed as fast as two weeks, with demonstrated safety profile that requires no lab monitoring1 1.7 million people in US live with CSU; more than half remain symptomatic despite increasing doses of antihistamines2,3Remibrutinib also in clinical development for chronic inducible urticaria, food allergy, and ...
Novartis receives FDA approval for Rhapsido® (remibrutinib), the only oral, targeted BTKi treatment for chronic spontaneous urticaria (CSU)
Globenewswire· 2025-09-30 20:15
Ad hoc announcement pursuant to Art. 53 LR Rhapsido helps to inhibit release of histamine and proinflammatory mediators by targeting BTK, offering unique approach to CSU treatment1Well-controlled disease observed as fast as two weeks, with demonstrated safety profile that requires no lab monitoring1   1.7 million people in US live with CSU; more than half remain symptomatic despite increasing doses of antihistamines2,3Remibrutinib also in clinical development for chronic inducible urticaria, food allergy, a ...
Healthy Returns: Pfizer's new obesity bet, Metsera, releases encouraging data on lead drug
CNBC· 2025-09-30 19:39
辉瑞收购Metsera及其肥胖症药物管线 - 辉瑞公司将以高达73亿美元的交易收购减肥药制造商Metsera 此项交易包括未来付款 预计在今年年底完成 [2] - Metsera成立于2022年 拥有针对不同靶点的口服和注射治疗药物管线 其最领先的候选药物是注射剂MET-097i [3] - MET-097i属于GLP-1类药物 与诺和诺德的Wegovy和礼来的Zepbound属同一类别 公司正开发每月注射一次的版本 可能比目前主导市场的每周注射剂更具便利性优势 [4] MET-097i中期试验疗效数据 - 在名为VESPER-1的中期试验中 最高剂量注射剂在28周后平均体重减轻高达141% 部分参与者体重减轻最高达265% [6] - VESPER-1的一项扩展研究显示 在36周时体重出现“显著且持续的减轻” 意味着尚未出现平台期 [7] - 与已上市药物相比 MET-097i的数据令人鼓舞 Wegovy在大型三期试验68周后体重减轻约15% Zepbound在后期研究中显示体重减轻超过20% [8] - 另一项试验VESPER-3正在研究每月注射一次 初步体重减轻数据预计在2025年底或2026年初公布 [9] MET-097i的安全性与耐受性 - 在两项试验中 起始剂量04毫克时 其注射剂的耐受性与安慰剂相当 [11] - 在VESPER-3试验中 患者在12周内逐渐增加剂量至12毫克 观察到“腹泻很少 恶心和呕吐仅轻微增加” 恶心和呕吐发生率分别比安慰剂组高13%和11% [12] - 即使在未逐步增加剂量的较高剂量下 其副作用与其他已批准的减肥药相当 VESPER-1试验中因副作用停止治疗的患者比例仅为29% 即239名患者中有2名 该停药率令人鼓舞 [13] 市场潜力与行业观点 - 摩根大通分析师认为MET-097i是新兴竞争对手之一 相信其将逐步从礼来和诺和诺德手中夺取部分市场份额 [5] - Leerink Partners分析师估计 Metsera的肥胖症候选药物有潜力产生超过50亿美元的合并年销售额峰值 [14] 医疗保险优势市场动态 - 健康保险公司在2026年的医疗保险优势计划中正优先考虑盈利能力而非增长 因会员医疗成本高于预期以及监管报销变化侵蚀了利润 [16] - 医疗保险与医疗补助服务中心预计 部分计划供应的收缩可能导致明年医疗保险优势注册人数下降 这将是十多年来的首次下降 [17] - 保险经纪商认为这可能是十多年来最具颠覆性的注册期之一 保险公司优先选择提供者网络限制更严的计划 并完全取消利润较低计划的佣金 超过70%被取消的计划是PPO [18] - 分析师指出区域保险公司也在采取类似举措 这可能成为市场中的不确定因素 若区域公司大量退出医疗保险优势 将因定价错误风险增加而给全国性计划带来意外增长 [19]
3 Pharma Stocks Getting an Intraday Trump Bump
Schaeffers Investment Research· 2025-09-30 19:19
Pharmaceutical stocks are enjoying tailwinds today, after President Donald Trump announced the launch of a direct-to-consumer website dubbed "TrumpRX." The new platform will enable Americans to buy their prescription drugs straight from the federal government. The White House said "virtually all drugs" would be available, with an 80% price discount for many of them. The White House made the announcement alongside Pfizer Inc (NYSE:PFE) CEO  Albert Bourla. The company is expected to lower drug prices for Medi ...
Eli Lilly in negotiations with Trump administration for the next pharma deal
Youtube· 2025-09-30 19:12
Well, I got some breaking news out of the White House, which means we're going to go to Aean Jabvers. Aean, >> Brian, uh, Eli Liy is the company that is in negotiations with the White House for a pharma deal similar to the one uh that Fizer struck earlier today that confirmed by the White House to me just within the past couple of moments. You can see uh Lily shares there have been moving throughout the day.That's because the president mentioned the company in the Fizer event. He said how terrific Eli Liy h ...
AbbVie Begins Construction on $70 Million Expansion to Further Increase Biologics Manufacturing and R&D Presence in the U.S.
Prnewswire· 2025-09-30 19:00
Accessibility StatementSkip Navigation NORTH CHICAGO, Ill., Sept. 30, 2025 /PRNewswire/ -- AbbVie (NYSE: ABBV) today announced the start of construction of a $70 million expansion at its AbbVie Bioresearch Center (ABC) in Worcester, Mass., which serves as a center of excellence for biologics research and development and manufacturing. This expansion is part of the company's previously announced commitment to invest more than $10 billion of capital in the U.S. to broadly support innovation and expand criti ...
BTIG Reiterates a Buy Rating on Viking Therapeutics (VKTX) With a $125 PT
Yahoo Finance· 2025-09-30 18:49
Viking Therapeutics, Inc. (NASDAQ:VKTX) is one of the best strong buy stocks to invest in according to Wall Street. On September 22, BTIG analyst Justin Zelin reiterated a Buy rating on Viking Therapeutics, Inc. (NASDAQ:VKTX) and set a $125.00 price target. Viking Therapeutics (VKTX) Soars 9.7% on Looming Weight Loss Drug Trial Results The analyst based the optimistic rating on the company’s strong position in the obesity and metabolic disease market, reasoning that the recent acquisitions conducted by t ...