PresentationI would now like to turn the call over to Laurence Watts of New Street Investor Relations. Please go ahead.Hello, and welcome to the Immuneering conference call to discuss the positive 9-month update announced last week from the company's ongoing Phase IIa trial of atebemetinib and first-line pancreatic cancer patients. [Operator Instructions] As a reminder, this call is being recorded today, Monday, September 29, 2025.Laurence Watts Thank you, operator. Joining us on the call today from Immunee ...

NEW YORK, Sept. 26, 2025 (GLOBE NEWSWIRE) -- Immuneering Corporation (Nasdaq: IMRX), a clinical-stage oncology company focused on keeping cancer patients alive, today announced that it will host a conference call and live webcast at 8:30 am ET on September 29, 2025, to discuss recently announced updated overall survival and safety data in first-line pancreatic cancer patients treated with atebimetinib + mGnP (N=34) with 9 months median follow up. “These exciting results were first announced in our press rel ...

Jay Olson from Oppenheimer sets a price target of $30 for Immuneering Corporation (NASDAQ:IMRX), indicating a significant potential upside.Immuneering announces an underwritten public offering of 18.96 million shares, aiming to raise approximately $175 million.The company's stock shows volatility, with a current decrease of 13.33%, amidst its efforts to strengthen its financial position through strategic financial activities.On September 25, 2025, Jay Olson from Oppenheimer set a price target of $30 for Imm ...

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盘前交易概况 - 美东时间周四上午7:35盘前交易出现显著活跃 多只股票呈现价格异动[1] - 盘前价格变动可能预示开盘后潜在交易机会 包括突破、反转或剧烈波动[1] - 早盘动量通常延续至常规交易时段 使盘前分析成为交易日关键组成部分[1] 涨幅显著股票 - PepGen Inc (PEPG) 股价上涨151%至6.68美元 位列涨幅榜首[3] - 22nd Century Group Inc (XXII) 上涨27%至1.93美元 涨幅排名第二[3] - Immuneering Corporation (IMRX) 上涨23%至11.36美元 位列涨幅第三[3] - uniQure N.V. (QURE) 上涨10%至52.58美元 锂业公司Lithium Americas Corp (LAC)同步上涨9%至6.60美元[3] - Jasper Therapeutics Inc (JSPR) 上涨9%至2.55美元 American Shared Hospital Services (AMS) 上涨8%至2.75美元[3] - PSQ Holdings Inc (PSQH) 上涨7%至3.06美元 K Wave Media Ltd (KWM) 同步上涨7%至2.48美元[3] - ClearPoint Neuro Inc (CLPT) 上涨5%至20.48美元 跻身涨幅前十[3] 跌幅显著股票 - Transocean Ltd (RIG) 下跌14%至3.11美元 领跌盘前交易[4] - Cyclerion Therapeutics Inc (CYCN) 下跌12%至2.83美元 跌幅排名第二[4] - CarMax Inc (KMX) 下跌11%至50.38美元 ARB IOT Group Limited (ARBB) 同步下跌11%至10.45美元[4] - SHF Holdings Inc (SHFS) 下跌10%至6.49美元 Digital Brands Group Inc (DBGI) 同步下跌10%至6.21美元[4] - Aqua Metals Inc (AQMS) 下跌9%至5.29美元 Akanda Corp (AKAN) 下跌8%至3.96美元[4] - Galecto Inc (GLTO) 下跌8%至3.88美元 Platinum Analytics Cayman Limited (PLTS) 下跌7%至11.12美元[4]

NEW YORK, Sept. 25, 2025 (GLOBE NEWSWIRE) -- Immuneering Corporation (Nasdaq: IMRX), a clinical-stage oncology company focused on keeping cancer patients alive, today announced the pricing of its underwritten public offering of 18,959,914 shares of its Class A common stock at an offering price of $9.23 per share, which is equal to the last reported sale price for Immuneering’s Class A common stock on The Nasdaq Global Market on September 24, 2025. In addition, Immuneering has granted the underwriters a 30-d ...

NEW YORK, Sept. 24, 2025 (GLOBE NEWSWIRE) -- Immuneering Corporation (Nasdaq: IMRX), a clinical-stage oncology company focused on keeping cancer patients alive, today announced a proposed underwritten public offering of shares of its Class A common stock or, in lieu of Class A common stock, pre-funded warrants to purchase Class A common stock (the “Offering”). In addition, Immuneering intends to grant the underwriters a 30-day option to purchase up to a number of additional shares of Class A common stock eq ...

- 86% overall survival (OS) observed at 9 months; standard of care benchmark is ~47% - - 53% progression-free survival (PFS) observed at 9 months; standard of care benchmark is ~29% - - Company expects regulatory feedback on pivotal trial plans in Q4 2025 and, subject to that feedback, expects to initiate pivotal trial by the end of 2025 and begin dosing patients by mid-2026 - NEW YORK, Sept. 24, 2025 (GLOBE NEWSWIRE) -- Immuneering Corporation (Nasdaq: IMRX), a clinical-stage oncology company focused on k ...

公司人事任命 - Immuneering Corporation宣布任命Thomas J Schall博士为董事会主席[1] - Schall博士是知名生物技术高管和科学家 拥有超过30年药物发现和开发领导经验[2] - 其曾担任ChemoCentryx创始人兼CEO 领导开发并获得FDA批准首创新药Tavneos® 该公司于2022年被安进以近40亿美元收购[2] 新任主席背景与价值 - Schall博士自2024年3月起担任公司董事 具备科学远见 运营纪律和监管敏锐度的独特组合[4] - 首席执行官Ben Zeskind认为其首创新药开发及从早期科学到商业化的专业经验将推动atebimetinib晚期开发[3] - 此次任命标志着公司准备进入新执行阶段 包括关键研究 注册申报和最终商业化[4] 研发进展与数据披露 - 公司主要候选产品atebimetinib是一种口服每日一次MEK深度循环抑制剂 旨在改善耐久性和耐受性[5] - 该药物目前处于2a期试验 针对晚期实体瘤包括胰腺癌患者[5] - 公司将于9月25日公布一线胰腺癌患者atebimetinib联合mGnP治疗的2a期研究更新数据 中位随访期9个月 并在9月28日胰腺癌行动网络年度科学峰会上展示[3] 公司战略与前景 - Immuneering致力于开发全新类别癌症药物Deep Cyclic Inhibitors 专注于延长癌症患者生存[5] - Schall博士认为公司有潜力重新定义癌症治疗的患者和医生期望[5] - atebimetinib目标是将适应症扩展到MAPK通路驱动肿瘤 如大多数胰腺癌[5]

公司数据发布计划 - 计划于2025年9月25日东部时间上午8点举行投资者电话会议 宣布一线胰腺癌患者使用atebimetinib联合mGnP治疗的更新总生存期数据（N=34） 中位随访时间达9个月 [1][6] - 将在2025年PanCAN科学峰会（9月28日）进行数据展示 海报标题为"Atebimetinib + mGnP: Overall Survival and Safety in First Line Pancreatic Cancer Patients" 展示时段为东部时间7:30-8:20和12:20-13:10 [6] - 将于2025年9月17日在第7届RAS靶向药物开发峰会上进行口服报告 主题为"Deep Cyclic Inhibition of MEK: A Transformational Approach to Durable and Safe Combinations in RAS-Mutant Cancers" 报告时间为东部时间16:15 [6] 临床数据表现 - 一线胰腺癌患者使用atebimetinib联合mGnP治疗6个月总生存率达到94% 显著高于标准护理方案GnP的67% [3] - 标准护理方案GnP治疗9个月时总生存率急剧下降至约47% 而atebimetinib组合9个月中位随访数据即将公布 [3] - 药物设计注重持久性和耐受性 旨在帮助患者延长生存期且避免严重副作用 [3] 产品研发进展 - 主要候选产品atebimetinib（IMM-1-104）是口服每日一次的MEK深度循环抑制剂 目前处于治疗晚期实体瘤（包括胰腺癌）的2a期临床试验阶段 [4] - 开发管线包含早期阶段项目 专注于开发全新癌症药物类别——深度循环抑制剂 [4] - 公司专注于MAPK通路驱动肿瘤的治疗 其中胰腺癌为主要适应症方向 [4] 行业会议参与 - 将在两个重要科学会议上进行展示：2025年PanCAN科学峰会和第7届RAS靶向药物开发峰会 [1][6] - 通过行业会议分享临床前数据深度循环抑制剂的研究成果 [5][6] - 与胰腺癌行动网络（PanCAN）合作 向肿瘤学界传递最新治疗进展 [3]