As filed with the Securities and Exchange Commission on December 5, 2025. Registration No. 333-291817 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 AMENDMENT NO. 1 TO FORM F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 CLEARMIND MEDICINE INC. (Exact name of registrant as specified in its charter) | British Columbia | 2834 | Not Applicable | | --- | --- | --- | | (State or other jurisdiction of | (Primary Standard Industrial | (I.R.S. Employer | | incorporation or organiz ...

股权与股价 - 待售普通股数量为5781250股[8,9,11] - 2024注册声明原涵盖可转售普通股数量为1126480股[10] - 2025年11月25日，纳斯达克公司普通股销售价格为0.16美元[13] - 2025年11月25日，法兰克福证券交易所公司普通股销售价格为0.1684欧元（约0.19美元）[13] - 目前已发行和流通的普通股为33181024股，假设行使2024年1月PIPE认股权证后将发行和流通38962274股[66] 财务状况 - 截至2025年7月31日，公司股东权益为负106.5668万美元，不符合纳斯达克最低股东权益250万美元要求[44][45][81] - 截至2025年7月31日，公司现金及现金等价物实际为349.5万美元，预计为1012.8万美元[98] - 过去三年，公司发行普通股净收益为1090万美元，认股权证行使获总收益530万美元[113] 融资情况 - 2025年9月17日，公司可发行最高1000万美元可转换本票，已发行250万美元并转换为517.146万股普通股[48] - 2025年11月，公司三次注册直接发行普通股和预融资认股权证，分别募资约78.8万美元、137.7万美元和218.5万美元[48][49][50][51] - 截至2025年11月14日，投资者行使认股权证获约18.3万美元收益[52] - 若2024年1月PIPE认股权证对应额外股份全部现金行使，公司将获约116万美元收益[89] 业务研发 - 公司CM - CMND - 001临床试验于2024 - 2025年逐步推进，涉及以色列和美国多地临床点[31] - 公司MEAI分子研究显示其可能对AUD、肥胖和代谢紊乱等有治疗作用[34][40] - 公司拟通过FDA 505(b)(1)监管路径为MEAI寻求监管批准[38] 其他事项 - 自2022年11月1日起，公司报告货币和功能货币为美元[22] - 2022年9月30日和2023年11月28日，公司进行两次1比30的已发行和流通普通股合并[25] - 2025年11月3日，公司收到纳斯达克通知，需在12月18日前提交恢复合规计划[44][46] - 公司作为新兴成长公司，最长可豁免至2027年12月31日[61] - 公司部分业务在以色列，当地状况可能影响运营、供应链和财务状况[72] - 公司需支付证券注册相关费用，预计总费用（不含配售代理折扣）为40,156美元[191]

As filed with the Securities and Exchange Commission on September 13, 2023. Registration No. 333-273293 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 AMENDMENT NO. 2 TO FORM F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 CLEARMIND MEDICINE INC. (Exact name of registrant as specified in its charter) | British Columbia | 2834 | Not Applicable | | --- | --- | --- | | (State or other jurisdiction of | (Primary Standard Industrial | (I.R.S. Employer | | incorporation or organ ...

As filed with the Securities and Exchange Commission on July 25, 2023. Registration No. 333-273293 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 CLEARMIND MEDICINE INC. (Exact name of registrant as specified in its charter) | British Columbia | 2834 | Not Applicable | | --- | --- | --- | | (State or other jurisdiction of | (Primary Standard Industrial | (I.R.S. Employer | | incorporation or organization) | Classification Code Number) | Identification Number) | 101 – 1220 West 6 Avenue Vancouver, B ...

As filed with the Securities and Exchange Commission on July 17, 2023. Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 CLEARMIND MEDICINE INC. (Exact name of registrant as specified in its charter) British Columbia 2834 Not Applicable (State or other jurisdiction of incorporation or organization) (Primary Standard Industrial Classification Code Number) (I.R.S. Employer Identification Number) 101 – 12 ...

As filed with the Securities and Exchange Commission on March 28, 2023. Registration No. 333-270859 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 AMENDMENT NO. 1 TO FORM F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 CLEARMIND MEDICINE INC. (Exact name of registrant as specified in its charter) | British Columbia | 2834 | Not Applicable | | --- | --- | --- | | (State or other jurisdiction of | (Primary Standard Industrial | (I.R.S. Employer | | incorporation or organizat ...

As filed with the Securities and Exchange Commission on March 27, 2023. Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 CONFIDENTIAL SUBMISSION ON FORM F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 CLEARMIND MEDICINE INC. If any of the securities being registered on this form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act, check the following box. ☒ If this form is filed to register additional securit ...