PEMBROKE, Bermuda, Jan. 08, 2026 (GLOBE NEWSWIRE) -- AXIS Capital Holdings Limited (“AXIS Capital” or the “Company”) (NYSE: AXS) today announced that it expects to release financial results for the fourth quarter ended December 31, 2025 on Wednesday, January 28, 2026 after the close of the financial markets. Vince Tizzio, President and Chief Executive Officer, and Peter Vogt, Chief Financial Officer, will host an investor teleconference, including a question and answer period, on Thursday, January 29, 2026 ...

INDIANAPOLIS, Jan. 08, 2026 (GLOBE NEWSWIRE) -- Kite Realty Group (NYSE: KRG) announced today that it will release financial results for the quarter ending December 31, 2025, before the market opens on Tuesday, February 17, 2026. KRG will conduct a conference call to discuss its financial results on Tuesday, February 17, 2026 at 11:00 a.m. Eastern Time. KRG Q4 2025 Earnings Conference Call Dial-In Registration: KRG Fourth Quarter 2025 Teleconference Registration Webcast Link: KRG Fourth Quarter 2025 Webcast ...

HUNTINGTON BEACH, Calif., Jan. 08, 2026 (GLOBE NEWSWIRE) -- BJ’s Restaurants, Inc. (NASDAQ: BJRI) announced today that the management team will be participating in a fireside discussion at the 28th Annual ICR Conference on Monday, January 12, 2026, starting at 8:00 AM ET. The Company will also meet with institutional investors during the conference, which will be held in Orlando, FL. A live webcast of the discussion will be available on the “Investors” page of the Company’s website located at https://invest ...

TOKYO, Jan. 08, 2026 (GLOBE NEWSWIRE) -- MEDIROM Healthcare Technologies Inc. (Headquarters: Minato-ku, Tokyo; CEO: Kouji Eguchi; NASDAQ: MRM, MEDIROM or the “Company”), announces that the cumulative number of Proof of Human authentications using the World ID authentication device ‘Orb’ at stores centered on the relaxation salon “Re.Ra.Ku,” operated by its subsidiary MEDIROM Wellness Co., surpassed 20,000 as of December 28, 2025. The Company participates in World (a Proof of Human authentication protocol), ...

Acquisition and Sale of VLCCs Frontline plc (“Frontline”) (NYSE: FRO – OSE: FRO) announces a strategic fleet renewal initiative, involving both the acquisition of new vessels and the sale of older vessels. Sale of eight of its oldest 1st generation ECO VLCCs The Company has entered into an agreement to sell eight of its oldest 1st generation ECO Very Large Crude Carriers (VLCCs), built between 2015 and 2016. These vessels are being sold for a total sales price of $831.5 million, with delivery to the new ow ...

NEWTON, Kan., Jan. 08, 2026 (GLOBE NEWSWIRE) -- Park Aerospace Corp. (NYSE – PKE) announced that it plans to release its financial results for its 2026 fiscal year third quarter ended November 30, 2025 after the New York Stock Exchange closes on Tuesday, January 13, 2026. The Company will conduct a conference call to discuss such results at 5:00 p.m. EST on the same day. Forward-looking and other material information may be discussed in this conference call. The conference call dial-in number is (877) 407-3 ...

公司财务信息发布安排 - 公司预计在2026年1月27日市场收盘后发布2025年第四季度及全年财务业绩 [1] - 管理层将于2026年1月28日东部时间上午11:00召开电话会议回顾业绩 会议可能讨论公司发展、前瞻性声明及其他重要业务和财务信息 [1] - 投资者可通过拨打电话(800) 330-6710 使用参会码6983606接入NBHC 2025年第四季度业绩电话会议 [1] - 电话会议录音将在结束后约4小时于公司官网投资者关系区域发布 [1] 公司业务概况 - 公司是一家银行控股公司 旨在打造领先的社区银行特许经营机构 致力于提供高质量客户服务并关注利益相关者成果 [2] - 公司通过其银行子公司NBH Bank和Bank of Jackson Hole Trust运营 拥有超过100个银行中心网络 [2] - 银行中心位于其核心区域 包括科罗拉多州、大堪萨斯城地区、德克萨斯州、犹他州、怀俄明州、新墨西哥州和爱达荷州 [2] - 其综合性住宅抵押银行业务主要服务于银行的核心区域 [2] - 信托业务在其核心区域以Bank of Jackson Hole Trust章程运营 [2] 公司品牌与运营架构 - NBH Bank通过单一州章程运营 旗下拥有多个品牌作为其部门 [2] - 在科罗拉多州 运营品牌为Community Banks of Colorado和Community Banks Mortgage [2] - 在堪萨斯州和密苏里州 运营品牌为Bank Midwest和Bank Midwest Mortgage [2] - 在德克萨斯州 运营品牌为Vista Bank和Hillcrest Bank [2] - 在犹他州、新墨西哥州和爱达荷州 运营品牌为Hillcrest Bank和Hillcrest Bank Mortgage [2] - 在怀俄明州 运营品牌为Bank of Jackson Hole和Bank of Jackson Hole Mortgage [2] 客户群体与联系信息 - 公司服务于个人消费者、中小大型企业以及政府和非营利实体 [2] - 更多信息可通过访问公司及其品牌网站获取 包括cobnks.com, bankmw.com, hillcrestbank.com, bankofjacksonhole.com, vistabank.com, 或 nbhbank.com [3] - 也可通过LinkedIn与其任何品牌联系 [3] - 投资者关系联系人为首席会计官兼投资者关系总监Emily Gooden 电话720-554-6640 邮箱ir@nationalbankholdings.com [4] - 媒体联系人为首席营销官Jody Soper 电话303-784-5925 邮箱Jody.Soper@nbhbank.com [4] - 首席财务官Nicole Van Denabeele的联系电话为720-529-3370 投资者关系邮箱为ir@nationalbankholdings.com [4]

文章核心观点 公司2025年在核心产品tegoprubart的临床开发中取得多项关键里程碑 包括在肾脏同种异体移植、胰岛移植和异种移植领域 其公布的二期BESTOW试验数据展示了良好的疗效、安全性和耐受性 支持该产品进入三期临床开发 同时公司完成了5750万美元的融资 为运营提供了资金保障 并规划了2026年的一系列业务里程碑[1][2][3] 2025年关键成就总结 - **肾脏移植二期BESTOW试验数据积极**：在2025年美国肾脏病学会肾脏周上公布的数据显示 tegoprubart安全性及耐受性良好 减少了与他克莫司相关的代谢、神经和心血管毒性 接受治疗的患者12个月时平均估算肾小球滤过率为69 mL/min/1.73 m² 公司认为这是大型肾脏移植临床试验中报告的最高平均eGFR水平 疗效失败复合终点（包括排斥率）在tegoprubart组为22.2% 他克莫司组为17.2% 使用20%的非劣效界值证明了tegoprubart不劣于他克莫司 数据支持其进入三期临床开发[3] - **胰岛移植初步结果积极**：在芝加哥大学医学中心主导的研究者发起试验中 首批6名接受胰岛移植的1型糖尿病患者使用tegoprubart作为核心免疫抑制剂 所有6名患者在一或两次移植后均实现胰岛素独立且血糖控制显著改善 其中前3名患者在移植后保持无胰岛素状态超过一年 结果显示无需使用他克莫司等钙调神经磷酸酶抑制剂即可预防胰岛排斥 并维持无胰岛素状态下的HbA1c控制 截至目前 共有8名患者使用tegoprubart作为核心免疫抑制剂接受了胰岛移植 另有一名因CNI相关肾毒性患者从他克莫司转为使用tegoprubart[3] - **异种移植中的应用**：tegoprubart被用作免疫抑制治疗方案的关键组成部分 用于马萨诸塞州总医院与eGenesis合作进行的基因编辑猪肾异种移植患者 这是tegoprubart第四次用于猪到人的异种移植 也是其在MGH的第三次使用[3] - **完成融资**：公司完成了5750万美元的承销公开发行 预计这笔资金将支持公司运营至2027年第二季度[1][3] 2026年预期里程碑 - **公布长期数据**：计划在2026年美国移植外科医生学会冬季研讨会上公布肾脏移植一期扩展研究中8名患者的24个月数据[4] - **推进三期临床试验**：预计将获得美国FDA关于肾脏移植三期试验设计的指导 并在与监管机构达成一致后启动三期试验[7] - **报告多项研究更新**：计划报告肾脏移植一期和二期BESTOW研究的长期数据 报告芝加哥大学医学中心胰岛细胞移植研究中1型糖尿病患者的更新数据 并获得FDA关于tegoprubart在胰岛细胞移植和异种移植中上市路径的监管指导[7] - **启动新的研究者发起研究**：计划启动三项新的研究者发起研究 分别评估tegoprubart在肾功能不全患者接受胰岛细胞移植、新接受肝移植患者以及肾脏移植耐受诱导中预防器官排斥的效果[7] 公司及产品背景 - **公司定位**：公司是一家临床阶段生物技术公司 致力于开发用于管理和治疗危及生命疾病的免疫调节疗法[5] - **核心产品**：主要在研产品是tegoprubart 一种高亲和力的抗CD40L抗体 CD40L是一个经过充分验证的生物靶点 在适应性和先天性免疫细胞激活及功能中起核心作用 具有广泛的治疗潜力 公司基于对抗CD40L生物学的深入了解 正在肾脏同种异体移植、异种移植、胰岛细胞移植和肌萎缩侧索硬化症领域进行临床前和临床研究[5]

SAN DIEGO, Jan. 08, 2026 (GLOBE NEWSWIRE) -- LPL Financial Holdings Inc. (Nasdaq: LPLA) (the “Company”), the parent corporation of LPL Financial LLC, announced today it will report fourth quarter and full year financial results after the market closes on Thursday, January 29. The Company will host a conference call to discuss its results at 5 p.m. ET the same day.The conference call will be accessible and available for replay at investor.lpl.com/events. Contacts Investor Relationsinvestor.relations@lplfinan ...

SAN DIEGO, Jan. 08, 2026 (GLOBE NEWSWIRE) -- Resmed (NYSE: RMD, ASX: RMD) today announced it plans to release financial and operational results for the second quarter of fiscal year 2026 on Thursday, January 29, 2026, after the New York Stock Exchange closes. Following the release, Resmed management will host a webcast to discuss the results. Other forward-looking and material information may also be discussed during the webcast. Earnings webcast details:•Location:https://investor.resmed.com•Date:Thursday, ...