As filed with the U.S. Securities and Exchange Commission on October 28, 2025 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SILO PHARMA, INC. (Exact name of registrant as specified in its charter) (State or other jurisdiction of incorporation or organization) If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the ...