Key Takeaways Fifth Third will acquire Comerica in an all-stock deal worth $10.9 billion, closing in early 2026.The impending merger expands FITB's footprint to 17 of the 20 fastest-growing U.S. markets. FITB targets$850M in annual cost synergies and expects the deal to lift EPS 9% by 2027. In one of the most consequential banking moves of 2025, Fifth Third Bancorp ((FITB) entered a definitive merger agreement to acquire Comerica Incorporated ((CMA) in an all-stock transaction valued at $10.9 billion. The ...